San Francisco to the Cayman Islands for only $293 roundtrip

_Grand Cayman / 1 Stop / American Airlines / Caribbean / Depart USA / Economy / Flight / San Francisco / San Francisco, USA → Grand Cayman, Cayman Islands / Standard Route
Flight deals from San Francisco to the Cayman Islands | Secret Flying

Cheap flights from San Francisco to the Cayman Islands for only $293 roundtrip with American Airlines.

 

DEPART:
San Francisco, USA

 

ARRIVE:
Grand Cayman, Cayman Islands

 

RETURN:
San Francisco, USA

 

DATES:
Availability from October 2025 to February 2026 (excluding Christmas/New Year)

Example dates:
21st-28th Oct
22nd-29th Oct
25th Oct – 1st Nov
29th Oct – 5th Nov
13th-20th Nov
17th-24th Nov
22nd-29th Jan
17th-24th Feb

and more…

 

STOPS:
Dallas

 

AIRLINES:
American Airlines

 

 

GO TO DEAL

 

Cheap flights from San Francisco to the Cayman Islands for only $293 roundtrip with American Airlines. Flight deal ticket image.

Find a hotel to go with your flight to
Grand Cayman