Non-stop from Rome, Italy to San Francisco, USA for only €499 roundtrip

_San Francisco / Deal / Depart Mainland Europe / Economy / Flight / Non-Stop / North America / Rome / Rome, Italy → San Francisco, USA / Standard Route
Flight deals from Rome, Italy to San Francisco, USA | Secret Flying
Missed the deal?

Become a Secret Flying member to receive alerts to your inbox the moment we publish a flight deal.

You'll never miss a Secret Flying deal again.

Non-stop flights from Rome, Italy to San Francisco, USA for only €499 roundtrip.

 

DEPART:
Rome, Italy

 

ARRIVE:
San Francisco, USA

 

RETURN:
Rome, Italy

 

DATES:
Limited availability from March to April 2026

Example dates:
23rd-31st Mar
31st Mar – 8th Apr

possibly more…

 

STOPS:

 

AIRLINES:
ITA Airways

 

 

GO TO DEAL

 

Non-stop flights from Rome, Italy to San Francisco, USA for only €499 roundtrip. Flight deal ticket image.

Top 10
Things to Do in
San Francisco

Check monthly
weather averages for

San Francisco
Find a hotel to go with your flight to
San Francisco