Chicago to Santa Cruz, Bolivia for only $446 roundtrip

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Cheap flights from Chicago to Santa Cruz, Bolivia for only $446 roundtrip with Copa Airlines.

DEPART:
Chicago, USA

ARRIVE:
Santa Cruz, Bolivia

RETURN:
Chicago, USA

DATES:
Availability from September to October 2025

Example dates:
16th-23rd Sep
16th-24th Sep
16th-25th Sep
17th-24th Sep
17th-25th Sep
23rd Sep – 2nd Oct
24th Sep – 2nd Oct
28th Sep – 6th Oct
5th-14th Oct
6th-14th Oct
6th-15th Oct
10th-17th Oct
10th-18th Oct
10th-19th Oct
11th-18th Oct
11th-19th Oct
11th-20th Oct
12th-19th Oct
12th-20th Oct
12th-21st Oct
17th-24th Oct
17th-25th Oct
17th-26th Oct
19th-26th Oct
19th-27th Oct
19th-28th Oct
20th-27th Oct
20th-28th Oct
20th-29th Oct
21st-28th Oct
21st-29th Oct
21st-30th Oct
23rd-30th Oct

and more…

STOPS:
Panama City

AIRLINES:
Copa Airlines