Detroit to Panama City, Panama for only $283 roundtrip

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Cheap flights from Detroit to Panama City, Panama for only $283 roundtrip with American Airlines.

DEPART:
Detroit, USA

ARRIVE:
Panama City, Panama

RETURN:
Detroit, USA

DATES:
Availability from June to October 2025 (excluding summer)

Example dates:
2nd-9th Sep
3rd-10th Sep
10th-17th Sep
12th-19th Sep
23rd-30th Sep
1st-8th Oct
–
More dates are available for $288 roundtrip:
19th-26th Jun
5th-12th Sep
9th-16th Sep
24th Sep – 1st Oct
30th Sep – 7th Oct
21st-28th Oct
22nd-29th Oct

and more…

STOPS:
Miami

AIRLINES:
American Airlines